Physical examination revealed left axillary swelling and tenderness with no localized skin or soft tissue lesions, particularly on the head, neck, chest, or left arm. The possibility of side effects was neglected, as the detection exceeded the expected time interval for an adverse reaction to the vaccine. She received the first and second doses of CoronaVac 5 and 4 months ago, respectively, with both doses delivered to the left deltoid muscle. She denied a medical history of allergic disease, tuberculosis, past malignant tumors, recent infection, trauma, specific medication history, and travel or social history. Case DescriptionĪ 34-year-old woman presented with left axillary pain for a week and transient fever (38.6☌) for a day. We highlight its prolonged course, discuss the clinical findings and imaging features, and analyze our misdiagnosis in combination with a relevant literature review. Herein we present a misdiagnosed case of remote lymphadenopathy after receiving the CoronaVac vaccine from Sinovac. This side effect is a frequent finding after COVID-19 vaccination. The frequency of imaging-detected lymphadenopathy ranged between 14.5 and 53% ( 12). The Centers for Disease Control and Prevention of the United States (CDC) have reported 11.6 and 16.0% of axillary swelling or tenderness after receiving the first and second doses of Moderna, respectively ( 11). In reality, the rate is likely to be higher. Additionally, it has been reported to be rare in the trials of Moderna, Novavax, Sinovac, Johnson & Johnson, and AstraZeneca vaccines ( 6– 10). Reactive hyperplasia of the ipsilateral axillary lymph nodes is a side effect of vaccination ( 3), which has been reported in 0.3% of the participants in the clinical trial of Pfizer ( 4, 5). As of February 10, 2022, 10.3 billion doses of the vaccines have been administered globally ( 2). Globally, large-scale COVID-19 vaccination programs are in progress to control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic ( 1).
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